GHK-Cu 50 mg

What it is

GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) that declines with age. It appears in cosmetic topical formulations in many markets.

Mechanism being studied

Research describes copper transport and modulation of genes associated with collagen and extracellular-matrix turnover in cell models.

Human evidence

There is a body of cosmetic-science literature on topical formulations reporting changes in skin appearance measures. Evidence for injectable or systemic use in people is not established.

Safety considerations

Safety information for this compound is incomplete outside of controlled settings. Reported considerations in the literature include injection-site reactions, unknown long-term effects, product-quality and sterility risks with unregistered preparations, and unpredictable interactions with existing medicines or conditions. Any consideration of use belongs with a registered healthcare professional who can assess the individual clinical picture.

Regulatory status

Topical cosmetic use is regulated under cosmetic rules in many markets; injectable presentations are not approved medicines. Confirm the status applicable in your jurisdiction.

Certificate of analysis

Third-party analytical documentation for this compound is published for transparency and professional review. It confirms identity and purity of tested material only, and is not a marketing authorisation, a registration, or a recommendation for use.

Key references

• Cosmetic-science peer-reviewed literature on GHK-Cu topical formulations.
• SAHPRA — medicines vs cosmetics classification guidance.

References are provided as reading directions for professionals. They do not constitute endorsement of any use.